View our most recent news articles detailing our work in the fields of flow chemistry, process engineering and more!
An efficient and safe transfer of chemistry from the laboratory to the plant scale requires process understanding. This understanding is provided by reaction calorimetric studies, an industrial standard practiced for years and typically done in batch operation. With the emerging flow chemistry applications, this standard will be and needs to be extended with flow calorimetry,… Continue Reading →
Microinnova has performed different halogenation reactions in the lab and has gained significant experience. For example, halogenation of aromatic systems with elemental halogens (fluorine, chlorine, bromine, iodine) or hydrohalogenation with hydro-halides has been carried out. “Flow process design and scale-up for safe and selective halogenation is a core competence of Microinnova.” says Dirk Kirschneck, Strategic… Continue Reading →
CordenPharma Chenôve SAS has commissioned a continuously operating modular API and intermediates synthesis plant that they recently put into operation to realize the benefits of process intensification. It consists of two feed modules with two dosing lines each, and four dosing lines altogether. Two of those dosing lines are made of Hastelloy, one is made… Continue Reading →
Based on nearly 20 years in the field of flow process design the team at Microinnova has executed more than 200 projects in flow chemistry. Different types of polymerization reactions have been executed including free-radical and ionic polymerizations, as well as polyester and oligomer synthesis. We address product quality and safety issues since these types… Continue Reading →
…by kicking off the Project “PharmComplete” using Digital Twin, Model-Predictive-Control and PAT strategies. A shift towards more efficient and controlled processes is taking place in the pharmaceutical industry with process analytical technologies, continuous manufacturing and advanced process control strategies being central elements. While different suppliers make plug and play lines available, especially in the field… Continue Reading →
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